SKLab @ UCSD

Evolution by natural selection is a fundamental property of life. I want to understand, predict and control how microbes evolve and adapt to their environment.

I am interested in how biotic interactions in microbial communities affect adaption. I currently study a simple community that consists of yeast S.cerevisiae and alga C.reinhardtii. I observe how these two species are adapting to living with each other.

I measure how the effects of mutations on fitness depend on the genetic background and on the environment in yeast Saccharomyces cerevisiae.

I am interested in population genetics and quantitative biology. My research question is: How does the proteome allocation changes in bacterium E.coli as it adapts?

I am interested in developing and testing models that predict the fitness effects of new mutations. I am also pursuing an improved lineage tracking system for long-term evolution experiments.

I am interested in using mathematical and computational models to understand evolution. I am currently working on a model to predict the evolution of cross-resistance and cross-sensitivity to antibiotics.

I am interested in systems biology, ecology and evolution. I’m currently working on understanding adaptation of modular organisms, using computer simulations and analytical theory.