Evolutionary Systems Biology

We are interested in uncovering general principles of how mutations affect phenotypes at multiple levels of biological organization (gene expression, metabolic fluxes, etc.), and how these effects combine to determine organism’s fitness across environments. We approach this problem using experiments in model microorganisms S. cerevisiae and E.coli (soon) and mathematical modeling.

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Lab news

October 20, 2016

First Microbial Experimental Evolution and Ecology (MEEE) meeting, a joint meeting between Daugherty, Dutton, Kryazhimskiy, and Meyer labs.

October 11, 2016

First SK Lab meeting! Georg presents his future project.

October 3, 2016

Dr. Sandeep Venkataram arrives from the Bay Area and joins the lab as a postdoc.

September 30, 2016

Hang Su finishes her internship. She made progress on RNAseq data analysis and the epistasis theory project.

September 19, 2016

Dr. Georg Rieckh arrives from Austria and joins the lab as a postdoc.
propagation of mutational effects
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